Polar’s ASAC Journey: Urgent Adjustments with CBD Oil, Turmeric, and Aloe Vera – Month Two Update

Polar Inu | $POLAR

Polar, my 10-year-old Siberian Husky soulmate, continues to storm through apocrine gland anal sac adenocarcinoma (ASAC), a rare cancer with a challenging prognosis (web:4,7). I’m Zaak, his caregiver, and we’re at month two of @MakisMD’s protocol (started March 30, 2025), with secondary tumors vanished and the primary site calmer as of May 26–28, 2025 (x.com/PolarInu_Solana). Beyond inflammation reduction, the primary and late bloomer sites aren’t shrinking noticeably—some days the primary site is flattened, others more raised, though not spiraling or seeding new tumors. With stability not guaranteed, we’re making urgent adjustments to push for #FirstRemission.

Here’s the latest!
Cutting-Edge Progress: Month Two on @MakisMD’s Protocol Polar’s fight leverages a protocol of ivermectin, fenbendazole, a ketogenic diet (60% fish, 40% pork), and topical DMSO with castor oil, inspired by @MakisMD and Dr. Thomas Seyfried. At month two, Polar’s secondary tumors are gone, the gland contour is restored, and there’s no spiraling or new tumor growth—a win for ASAC, which has a low remission rate of ~5–15% with standard care (e.g., surgery, radiotherapy, chemotherapy), depending on stage and metastasis (web:18,19,20). A deeper “late bloomer” site persists, stable with no bleeding. This mirrors @MakisMD’s recent lymphoma remission case (April 8, 2025, https://t.co/os5ga0cKja), placing Polar at the forefront of canine cancer care. The lack of consistent shrinkage beyond inflammation reduction signals a need for urgent action, as waiting risks ASAC’s aggressive nature (web:4).

Fine-Tuning DMSO and Application Schedule
We apply a 70/30 DMSO/castor oil mix in the AM, followed 1–2 minutes later by a paste, targeting Polar’s tumor sites. DMSO causes only slight warming with no irritation, showing good tolerability. We’ve kept pastes separate to ensure they set like paint:
AM Dose: 70/30 DMSO/castor oil mix (0.3ml: 0.21ml DMSO + 0.09ml castor oil) with 1–2 drops organic CBD oil (~5–10mg) and ~0.1g turmeric powder, wait 1–2 minutes, then ivermectin paste (0.5–0.75g, occasionally up to 1g) with 0.2g aloe vera gel.

Midday Dose: Fenbendazole paste only (0.5–0.75g, no DMSO, castor oil, CBD, or turmeric), maintaining consistent pressure on cancer cells.

PM Dose: If increasing to 2x daily DMSO, apply DMSO/castor oil mix with CBD oil and turmeric, wait 1–2 minutes, then ivermectin paste with aloe vera gel (0.5–0.75g, occasionally up to 1g); if 1x daily, apply ivermectin paste with 0.2g aloe vera gel and 1–2 drops castor oil.
Total daily topical paste is ~1.5–2.25g (up to 3g on higher days), split as ~0.5–1g ivermectin (AM), ~0.5–0.75g fenbendazole (midday), and ~0.5–1g ivermectin (PM). Before the full protocol on March 30, 2025, we used up to 1g per AM/PM dose to seal bleeding, a critical step when bleeding was unmanaged. Since introducing oral ivermectin, inflammation and blood volume in the tumors have dropped significantly, helping control bleeding, though we balance thorough application with the cost of maintaining both systemic and topical treatments. Oral ivermectin is reduced by 10–15% to account for DMSO’s absorption boost, staying within @MakisMD’s safe maximum of 0.5mg/kg/day. For Polar’s current weight of 23.8kg, this max is 11.9mg, reduced to ~10.1–10.7mg.

We’ll increase DMSO to 2x daily (AM/PM) on June 2, 2025, further reducing oral ivermectin by 10–15% (from 11.9mg to ~10.1–10.7mg). We’ll monitor for 2–4 weeks (June 2–June 16): if the tumor grows or inflammation increases, we’ll revert to the previous oral dose (11.9mg) and reduce DMSO to 1x daily (AM only); if the tumor shrinks or remains stable, we’ll continue 2x daily DMSO to enhance the protocol’s effectiveness.

Urgent Adjustment:
Enhancing Pre-Application with CBD Oil and Turmeric
With no noticeable shrinkage beyond inflammation reduction, and the primary site’s fluctuating appearance, waiting until July risks losing stability.

Starting May 30, 2025, we’re enhancing the AM/PM pre-application by adding organic CBD oil and turmeric to the DMSO/castor oil mix, followed by ivermectin paste with aloe vera gel. The pre-application mix (0.3ml) now includes 1–2 drops CBD oil (~5–10mg) and ~0.1g turmeric powder, applied before the paste (0.5–0.75g ivermectin with 0.2g aloe vera gel). The midday fenbendazole dose remains paste-only to avoid overloading. CBD oil and turmeric reduce inflammation and may inhibit tumor growth, addressing the stagnation while avoiding turmeric’s mess in the paste. DMSO enhances their penetration, and aloe vera ensures the paste sets for prolonged contact. We’ll monitor for 3–4 weeks (May 30–June 27) for shrinkage, inflammation changes, or irritation (e.g., redness, licking), expecting minimal risk given CBD’s safety (web:17).

pH Rocking: A Future Option
pH rocking—alternating bicarbonate soda and lemon applications—could disrupt the tumor microenvironment, as seen in an X post by @CancerWarrior21 (March 15, 2025), which reported 30% tumor shrinkage in a dog after two months. We’d mix bicarbonate soda (¼ tsp) with ivermectin paste (0.5g) for 4 days, then switch to a diluted lemon paste (1 tsp lemon juice with water, ½ tsp aloe vera) for 4 days, cycling for 2–3 weeks. However, lemon risks irritation, and the late bloomer site’s depth may limit topical pH effects. Given Polar’s stability, we’ll hold off unless the enhanced pre-application fails to yield progress by late June 2025, then trial pH rocking starting July 1, monitoring for irritation.

Fenbendazole Toxicity: A Low Risk
We apply 0.5–0.75g of fenbendazole paste topically at midday (50–75mg fenbendazole, up to 100mg on higher days), with Polar’s oral dose at above previously mentioned in our Steemit posts prior to @MakisMD’s protocol. With DMSO (AM only), ~15–25mg of topical fenbendazole is absorbed systemically (30–50% absorption rate), This is below toxicity thresholds (100mg/kg/day), with studies showing fenbendazole’s wide safety margin in dogs (web:14). Polar’s stable weight and lack of adverse effects (e.g., no vomiting, resolved bowel issues) confirm the low risk, but we’ll monitor closely given the higher mg/kg compared to a 30kg estimate.

Next Steps: Logical Path Forward
Polar’s stability is a triumph, but the lack of consistent shrinkage requires action now. Here’s the plan:
Enhance Pre-Application with CBD Oil/Turmeric (May 30): Add to AM/PM DMSO/castor oil mix, followed by ivermectin paste with aloe vera gel, monitoring for 3–4 weeks (May 30–June 27).

Increase DMSO to 2x Daily (June 2): If no adverse reactions by week 2, add a PM DMSO application, adjusting oral ivermectin. Monitor tumor size and inflammation weekly for 2–4 weeks.

Trial pH Rocking (July 1, If Needed): If no progress by late June, trial pH rocking with bicarbonate-ivermectin and lemon pastes, cycling every 4 days for 2–3 weeks, starting on the primary site and monitoring for irritation.

Extend @MakisMD’s Guidance: With $POLAR’s community support (103k ATH), we’ll aim to extend coaching beyond June, as timelines for remission can extend to 3–6 months (web:13).

Community Engagement: Share Polar’s updates with #PolarInuArmy to rally support, as $POLAR’s transparency (Solscan, Steemit) counters troll FUD calling us a “scam” or “rug pull.”

Join Polar’s Storm
Polar’s journey is a storm of hope, defying ASAC’s odds with love and innovation. Join #PolarInuArmy to support $POLAR and redefine canine cancer care!

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