I think most people would enjoy it, whether they have read the book or not. One of the best things about the series so far is that they haven't (yet) strayed from the source material too much but seeing as how they have already burned through about 70% of the book's overall content in the first season, and there are 3 or maybe 4 more seasons that have already been released I would imagine that they do stray a lot from it later.