It takes about 30 days before you really start noticing that you are feeling better according to my daughter and my husband. I haven't tired it myself, just know the results from both of them. Plus I have photos of my daughters intestines before and after pine nut oil and the difference is amazing. One of these days I will find the file as I finish unpacking and will do a post with what evidence I have on how it helped our daughter. The heartburn was helped nearly right away for my husband four or five days he noticed his heartburn was lessened